PRIORITIZE RELATIONSHIPS

“There was a really big trial called the BACE two trial that just came out in the last month. They looked at the 14 kind of consensus biomarkers that we know are really good at predicting mortality. Things like grip strength, IL six inflammatory stuff, standing balance, cognitive health, VO two max, muscle mass. Dunedin pace was the number one. It was above all of these other ones.”

“The fact that this Harvard study on healthy aging was eighty years and a thousand people, it is the definitive. So in my mind, the number one intervention over everything I'll ever tell you about, oh, they studied this supplement, they studied this medication. None of that is close to the strength of your social relationships. Anyone who's biohacking and not focusing on that, they're wasting their time with everything else.”

“In this Harvard study, they were saying, can we diagnose cardiovascular disease, OCD, these things? But they also asked another question. They said, can we also predict other biomarkers? We found 1,600 biomarkers we could predict. When we measured them against their traditional versions, about two thirds performed better.”

“We could do it all at once. What I'd say is, like, stay up all night and don't sleep. And while you're up, smoke as much as you can smoke. Be as stressed out as you can be, and then just overeat. Like, those are the biggest things. It's like excess calories, lack of sleep, stress, and then the things that we know like smoking and excess alcohol.”

“I just got an email today. We were doing a study with someone who was looking at Ayahuasca. A lot of the genes that were became hypomethylated post ayahuasca were genes related to neuroplasticity. And people talk about that neuroplastic window and those genes actually turned on, which was a fascinating outcome. BDNF, so genes that express BDNF were actually turned up too.”

“When I hear people talk about biologic age tests, quote, unquote, not being valid, I shake my head, yes, 90% aren't. There's four criteria that make a good biologic age test. Number one, it has to be published. Number two, it has to actually predict outcomes. The third thing is they have to be reliable. And the last thing is, these tests have to respond to interventions.”

“Your DNA makes it up about 20% of your health outcome, but the other 80% are what you do, what you eat, how you sleep, your stress levels. With epigenetics, you're measuring that. That other 80%, you're actually looking at how much every gene is turned up and turned down.”

“Somebody reached out to me and said they were gonna try this Guinness world record group speed attempt of up and down Kilimanjaro. I basically built an AI coach for myself that I would feed in all my true health data. The people who were on the climb with us, they were army ranger, special forces, delta force guys, famous ultra marathoners. They were way stronger than I was, but I was actually the first one to the top because I was so dialed into the science of I knew it's really an eating contest with a lot of hiking.”

“In this case, the February test was after an eighteen hour flight back from Munich, Germany testing the next morning, after arriving at about 11:30PM the night before. I had a different test through my doctor. I've had a history of elevated liver enzymes. So I thought, I'm gonna be lazier than I've ever been for a few years and just basically sit on the couch, hang out with my wife, stretch a little bit, and then go in and test. And the liver markers were pristine.”

“This is the most expensive sweatshirt I own. I was at a spa in Portugal, and the weather was colder than I thought. I just grabbed this one because it looked like the cheapest sweater in the joint. And as I was checking out, realized I'd spent $350 on a sweatshirt that says dad on it. It literally feels like a cheap champion sweatshirt. I think I just paid for the brand.”